DisCVR: Rapid viral diagnosis from high-throughput sequencing data
نویسندگان
چکیده
منابع مشابه
Characterizing Transcriptomes from High-Throughput Sequencing Data
The DNA in our cells contains our genetic hereditary information, and is literally the blueprint of our body. The functional units of the genome are regions of continuous DNA sequence, and are called genes. According to the Central Dogma of Biology, the DNA sequence of the gene is transcribed into a messenger RNA (mRNA), which is in turn translated to proteins, which perform most tasks in the c...
متن کاملPrevention, diagnosis and treatment of high-throughput sequencing data pathologies.
High-throughput sequencing (HTS) technologies generate millions of sequence reads from DNA/RNA molecules rapidly and cost-effectively, enabling single investigator laboratories to address a variety of 'omics' questions in nonmodel organisms, fundamentally changing the way genomic approaches are used to advance biological research. One major challenge posed by HTS is the complexity and difficult...
متن کاملBOOGIE: Predicting Blood Groups from High Throughput Sequencing Data
Over the last decade, we have witnessed an incredible growth in the amount of available genotype data due to high throughput sequencing (HTS) techniques. This information may be used to predict phenotypes of medical relevance, and pave the way towards personalized medicine. Blood phenotypes (e.g. ABO and Rh) are a purely genetic trait that has been extensively studied for decades, with currentl...
متن کاملIdentifying small interfering RNA loci from high-throughput sequencing data
MOTIVATION Small interfering RNAs (siRNAs) are produced from much longer sequences of double-stranded RNA precursors through cleavage by Dicer or a Dicer-like protein. These small RNAs play a key role in genetic and epigenetic regulation; however, a full understanding of the mechanisms by which they operate depends on the characterization of the precursors from which they are derived. RESULTS...
متن کاملDNA Methylation Profiling from High-Throughput Sequencing Data
The methylation of a cytosine at the carbon 5 position (5meC) is a common epigenetic mark in eukaryotic cells that is normally found in CpG and CpHpG (H=A,C,T) sequence contexts. The inactivation of one of the X-chromosomes in female cells, the allele-specific expression of imprinted genes or the role in the embryonic development which is shown by the early lethality of Dnmt3a and Dnmt3b defici...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Virus Evolution
سال: 2019
ISSN: 2057-1577
DOI: 10.1093/ve/vez033